This article showcases our top picks for the best France based Biotechnology companies. These startups and companies are taking a variety of approaches to innovating the Biotechnology industry, but are all exceptional companies well worth a follow.
We tried to pick companies across the size spectrum from cutting edge startups to established brands.
We selected these startups and companies for exceptional performance in one of these categories:
- Innovation
- Innovative ideas
- Innovative route to market
- Innovative product
- Growth
- Exceptional growth
- Exceptional growth strategy
- Management
- Societal impact
Top France Biotechnology Startups
Data sourced from Crunchbase and SemRush.
DNA Script
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DNA Script is a disruptive DNA synthesis company harnessing biology to accelerate breakthroughs in life science and human health.
Ynsect
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Ynsect provides products and services that operate in the agro-food and environmental biotech industries.
Valneva
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Valneva is a specialty vaccine company focused on prevention of infectious diseases with significant unmet medical need.
SparingVision
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SparingVision is a biotechnology company focused development of genomic medicines for the treatment of blinding inherited retinal diseases.
Sanofi
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Sanofi is engaged in the research, development, manufacturing, and marketing of innovative therapeutic solutions.
Egle Therapeutics
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Egle Therapeutics is a biotechnology company focused on developing immunotherapies for oncology and autoimmune diseases.
TreeFrog Therapeutics
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TreeFrog Therapeutics is a stem cell company that will enable millions of patients to access the medical revolution of cell therapies.
TISSIUM
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TISSIUM develops biodegradable sealants and adhesives for wound closure in the field of minimally-invasive surgery.
Amolyt Pharma
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Amolyt Pharma specializes in peptides for the treatment of rare endocrine and metabolic disorders.
InnovaFeed
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InnovaFeed is a biotech company producing insect-based protein for the feed industry.
Agronutris
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Agronutris is a biotech involved in the breeding and processing of insects for food.
Cellectis
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Cellectis is a biopharmaceutical company that develops adoptive immunotherapies for cancer.
Neovacs
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Neovacs, a biotech company, develops several therapeutic vaccines for the treatment of AIDS, cancer and auto-immune and allergic diseases.
Biogroup-LCD
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Biogroup-LCD is a player in local medical biology,supports more than 20,000 patients every day and offers more than 2000 routine.
HiFiBiO
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HiFiBiO provides proprietary single cell technologies for applications in drug and biomarker discovery and development.
Biophytis
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Biophytis is a research company that focuses on the fields of metabolic and age-related diseases.
Ipsen
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Ipsen develops and markets medications used in oncology, neuroscience and rare diseases along with consumer healthcare products.
Innate Pharma
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Innate Pharma is a biopharmaceutical company developing immunotherapy drug candidates for the treatment of cancer and inflammatory diseases.
erytech
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ERYtech Pharma is a biopharmaceutical company, develops enzyme-based medicinal products for the oncology, hematology and immunology sectors.
Stilla Technologies
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Stilla Technologies is a Paris-based european biotechnology company.
Pharnext
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Pharnext is a biopharmaceutical company engaged in the development of treatments for severe neurological diseases.
PKVitality
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PKvitality is an advanced bio-wearable company.
Alira Health
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Alira Health is an international advisory firm.
Carbios
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Carbios is a chemistry company that focuses on discovering and developing enzymatic bioprocesses applied to plastic and textile polymers.
ENTEROME
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Enterome is a clinical-stage company developing drugs for chronic medical conditions relating to abnormalities of bacterial composition.
Sanofi Pasteur
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Sanofi Pasteur SA develops, manufactures, and supplies vaccines in France and internationally.
Eyevensys
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Eyevensys creates ophthalmic therapeutic bio factories to sustainably treat major eye diseases.
Ceva Santé Animale
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Ceva Sante Animale is a veterinary health company focused on the research, development, production and marketing of pharmaceutical products.
Mauna Kea Technologies
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Mauna Kea Technologies specializes in designing, developing, and selling optical biopsy devices and tools.
OSE Immunotherapeutics
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OSE Immunotherapeutics is a clinical-stage biotechnology company focused on developing.
NOVACYT
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NOVACYT develops cellular diagnostics with a growing portfolio of cancer and infectious disease products and services.
GenSight Biologics
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GenSight Biologics develops gene therapy-based treatments for retinal degenerative diseases.
Eligo Bioscience
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Eligobiotics provides a new approach to explore, understand, and control bacterial ecosystems both in human and animals.
Dynacure
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Dynacure is a clinical-stage drug development company focused on improving the lives of patients with rare and orphan diseases.
Novadiscovery
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Health tech company using clinical trial simulation technology to predict drug efficacy and optimize clinical trial development.
Mnemo Therapeutics
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Mnemo Therapeutics specializes in biotechnology and life science.
Medicrea
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Medicrea is a fully-dedicated spinal implant company focused on introducing reliable and innovative technologies to the global marketplace.
Coave Therapeutics
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Coave Therapeutics is a clinical stage biotechnology company focused on developing life changing gene therapies in rare Ocular and CNS.
GENFIT
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GENFIT is a late-stage biopharmaceutical company.
AFYREN
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AFYREN develop innovation in biotechnologies for the valorization of non-food biomass and in respect of the environment.
Horama
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Horama develops gene therapies for rare inherited ocular diseases.
Transgene
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Transgene is a biotechnology company that designs and develops innovative immunotherapies.
ImCheck Therapeutics
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ImCheck Therapeutics is a developing novel therapeutics that target members of the butyrophilin (BTN) super-family of checkpoint molecules.
Acticor Biotech
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Acticor Biotech is a biopharmaceutical company developing an innovative drug for the treatment in the acute phase of ischemic stroke.
Pili
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PiLi biofabricates a sustainable alternative to create renewable inks to replace their toxic, non-biological, and non-recyclable versions.
nextProtein
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nextProtein develops a new large-scale technology that produces a sustainable source of protein.
MaaT Pharma
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MaaT Pharma (Microbiota as a Therapy) is a French biotech start-up.
Vivet Therapeutics
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Vivet Therapeutics is a biotechnology company developing gene therapy treatments for orphan diseases.
MedDay
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MedDay is a biotechnology company developing new drugs targeting brain metabolism.
Global Bioenergies
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Global Bioenergies develops a process for converting plant carbohydrates (sugar, cereals, agricultural waste) into hydrocarbons.
Innoskel
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InnoSkel is a pioneering platform biotechnology company developing therapies for rare skeletal diseases.
AB Science
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AB Science is a pharmaceutical company specializing in drugs use tyrosine kinase inhibitors.
Robocath
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Robocath is a medical robotics start-up company.
Microphyt
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Microphyt researches, develops, produces, and markets natural algae-based products that contribute to weight loss and to brain health.
SeqOne
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SeqOne is a next generation genomic analysis for next generation healthcare.
Poxel
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Poxel is a research integrated pharmaceutical company that develops products for metabolic diseases.
Flash Therapeutics
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Flash Therapeutics is a new gene therapy company developing gene and cell-based therapies by leveraging its proprietary lentiviral platform.
BforCure
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BforCure is a biotech engaged in the manufacture of high speed biosensing solutions such as CHRONOS PCR.
Biom’Up
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Biom’Up is a French company that specialises in the manufacture of re-absorbable medical devices based on collagen technology.
Theravectys
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Theravectys develops a platform for the prevention and treatment of cancers and other infectious diseases and conditions.
Echosens
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Echosens is an innovative high-technology company offering a full range of products and services supporting physicians.
Inotrem
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Inotrem is a biotechnology company specialized in immunotherapy for acute inflammatory syndromes, such as septic shock.
Lucine
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Lucine has the ambition to transform and improve patient’s health.
ARGOBIO
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Argobio SAS is a start-up studio for Therapeutics aiming to nurture and launch Biotech companies.
Sensorion
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Sensorion is a France-based biopharmaceutical company developing targeted therapeutic solutions for the treatment of vestibular deficits.
Agalaia Therapeutics
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Agalaia Therapeutics is a biotech specialized in the development of new therapies to combat cancer disease.
Inventiva Pharma
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Inventiva is a biopharmaceutical company with several drug candidates at clinical and preclinical stage.
Woodoo
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WOODOO bridges synthetic biology and organic chemistry to design patented, groundbreaking new materials.
Domain Therapeutics
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Domain Therapeutics develops small molecules targeting G-coupled protein receptors.
Fermentalg
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Fermentalg is engaged in the production of micro-algae for the agrifood, healthcare and energy markets.

Tribun Health, AI-Powered Pathology
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Tribun Health powers the digital transformation of cancer diagnosis by designing innovative solutions. These solutions enable the management, analysis and sharing of cellular images for both diagnostic laboratories and pharmaceutical and biotech companies. The company offers customized support in digital pathology, focused on the customer’s expectations.
In the field of image analysis, our solutions are based on the latest innovations in terms of artificial intelligence, notably deep and machine learning algorithms. These tools support physicians and researchers in their diagnostic decision-making and scientific evaluation for the sake of patients.
In the field of sharing, our solutions implement full web tools to support our customers in their telepathology, teaching or multi-centric clinical validation activities.
inHEART
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inHEART is providing a cloud-based medical image analysis solution for cardiac interventions on patients with arrhythmias.
Osivax
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Osivax is a clinical stage biotechnology company developing a pipeline of vaccines and immunotherapies.
CarThera
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CarThera designs and develops innovative therapeutic ultrasound-based medical devices for treating brain disorders.
LYSOGENE
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Lysogene is a pioneer in the basic research and clinical development of gene therapy for neurodegenerative disorders.
ENYO Pharma
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ENYO Pharma is a biopharmaceutical company based in Lyon, France.
Xenothera
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Xenothera is a xenotherapy platform with embedded technology that renovates immunological treatments.
Gaiago
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Gaiago is an agtech company that produces soil improvement tools.
Flamel Technologies
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Flamel Technologies is a pharmaceutical company, utilizing its core competencies in formulation development and drug delivery.
PathoQuest
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PathoQuest is a biotech company developing NGS-based metagenomic tests for exhaustive identification of pathogens.
Core Biogenesis
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Core Biogenesis is a biotechnology company building next-generation recombinant protein production technologies.
PDC*line Pharma
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PDC*line Pharma develops a new class of active immunotherapies for cancer based on an allogeneic cell line of Plasmacytoid Dendritic cells.
Micropep Technologies
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Micropep Technologies is a biotech company that focused on biological alternatives to agrochemicals.
Advicenne
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Advicenne is a specialty pharmaceutical company dedicated to improving the lives of patients who suffer from rare kidney diseases.
Antabio
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Antabio is a private biopharmaceutical company developing antibacterial resistance-breakers in areas of highest medical need.
Pherecydes Pharma
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Pherecydes Pharma Operator of an innovative biotechnologies company created to develop personalized phage therapy.
xRapid
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xRapid is a mobile health diagnosis through disruptive solutions leveraging the use of artificial intelligence.
Onxeo
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Onxeo is a biotechnology company that develops drugs for oncology.
EG 427
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EG 427 is a French biotechnology company that pioneers a new approach in gene therapy called pinpoint gene therapy.
SuperSonic Imagine
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SuperSonic Imagine develops and manufactures ultrasound medical imaging systems for evaluating and visualizing tissue elasticity.
Smart Immune
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Hematopoietic stem cell-based biotherapies
Scipio Bioscience
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A Paris-based biotechnology company .
Valbiotis
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Valbiotis develops nutrition solutions to prevent cardio metabolic diseases and provides nutritional support for patients.
METabolic EXplorer
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METabolic EXplorer is a biochemistry company that develops industrial alternatives to petrochemical processes.
Aelis Farma
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Aelis Farma is a biotech company conducting research and development on innovative signaling specific drugs
TargEDys
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TargEDys develops functional food, medical food and medical products to harness the microbiota’s ability to regulate appetite.
Japet Medical
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Japet Medical Devices is a French biomedical company developing robotic equipment for the most advanced quality of treatment.
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